Molecular Toxicology Protocols (Paperback, 2005)

A collection of cutting-edge techniques for analyzing genotoxic exposure and detecting the resulting biological effects-including endogenous metabolites-up to and including the development of cancer. The authors emphasize analytical methods that can be specifically applied to human populations and patients. Among the applications detailed are the analysis of interactions between such cellular macromolecules as DNA and proteins and chemical and physical agents, the assessment of medically relevant toxicity, and the characterization of genetic alterations induced in transgenic animals by in vivo systems. There are also methods for the analysis of genotoxic exposure during gene expression, of cytotoxicity caused by the induction of apoptosis, of genetic alterations in reporter genes and oncogenes, early (premalignant) detection of altered oncogenes, and of individual variation in biotransformation and DNA repair capacity.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 291
Release date:	October 2013
First published:	2005
Editors:	Phouthone Keohavong • Stephen G. Grant
Dimensions:	235 x 155 x 27mm (L x W x T)
Format:	Paperback
Pages:	489
Edition:	2005
ISBN-13:	978-1-61737-347-3
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Promotions
LSN:	1-61737-347-8
Barcode:	9781617373473

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