Recentyearshaveseentheadventanddevelopmentofmanydevicesabletorecordand
storeaneverincreasingamountofinformation.
Thefastprogressofthesetechnologies is ubiquitousthroughoutall ?elds
of science and applied contexts, ranging from
medicine,biologyandlifesciences,toeconomicsandindustry.
Thedataprovided
bytheseinstrumentshavedifferentforms:2D-3Dimagesgeneratedbydiagnostic
medicalscanners,computervisionorsatelliteremotesensing,microarraydataand
genesets,integratedclinicalandadministrativedatafrompublichealthdatabases,
realtimemonitoringdataofabio-marker,systemcontroldatasets.
Allthesedata
sharethecommoncharacteristicofbeingcomplexandoftenhighlydimensional.
Theanalysisofcomplexandhighlydimensionaldataposesnewchallengesto
thestatisticianandrequiresthedevelopmentofnovelmodelsandtechniques,fueling
manyfascinatingandfastgrowingresearchareasofmodernstatistics.
Anincomplete listincludes for example: functionaldata analysis,
that deals with data having a
functionalnature,suchascurvesandsurfaces;shapeanalysisofgeometricforms,that
relatestoshapematchingandshaperecognition,appliedtocomputationalvisionand
medicalimaging;datamining,thatstudiesalgorithmsfortheautomaticextraction
ofinformationfromdata,elicitingrulesandpatternsoutofmassivedatasets;risk
analysis,fortheevaluationofhealth,environmental,andengineeringrisks;graphical
models,thatallowproblemsinvolvinglarge-scalemodelswithmillionsofrandom
variableslinkedincomplexwaystobeapproached;reliabilityofcomplexsystems,
whoseevaluationrequirestheuseofmanystatisticalandprobabilistictools;optimal
designofcomputersimulationstoreplaceexpensiveandtimeconsumingphysical
experiments.
Thecontributionspublishedinthisvolumearetheresultofaselectionbasedonthe
presentations(aboutonehundred)givenattheconference"S. Co.
2009:Complexdata
modelingandcomputationallyintensivemethodsforestimationandprediction",held
? atthePolitecnicodiMilano. S. Co.
isaforumforthediscussionofnewdevelopments ? September14-16,2009.
Thatof2009isitssixthedition,the?rstonebeingheldinVenice in1999. VI
Preface
andapplicationsofstatisticalmethodsandcomputationaltechniquesforcomplexand
highlydimensionaldatasets.
Thebookisaddressedtostatisticiansworkingattheforefrontofthestatistical
analysisofcomplexandhighlydimensionaldataandoffersawidevarietyofstatistical
models,computerintensivemethodsandapplications.
Wewishtothankallassociateeditorsandrefereesfortheirvaluablecontributions
thatmadethisvolumepossible. MilanandVenice,May2010 PietroMantovan
PiercesareSecchi Contents
Space-timetextureanalysisinthermalinfraredimagingforclassi?cation
ofRaynaud'sPhenomenon
GrazianoAretusi,LaraFontanella,LuigiIppolitiandArcangeloMerla...1
Mixed-effectsmodellingofKevlar?brefailuretimesthroughBayesian
non-parametrics
RaffaeleArgiento,AlessandraGuglielmiandAntonioPievatolo...13
Space?llingandlocallyoptimaldesignsforGaussianUniversalKriging
AlessandroBaldiAntogniniandMaroussaZagoraiou...27
Exploitation,integrationandstatisticalanalysisofthePublicHealth
DatabaseandSTEMIArchiveintheLombardiaregion
PietroBarbieri,Niccolo'Grieco,FrancescaIeva,AnnaMariaPaganoniand
PiercesareSecchi...41 Bootstrapalgorithmsforvarianceestimationin
PSsampling AlessandroBarbieroandFulviaMecatti...5 7
FastBayesianfunctionaldataanalysisofbasalbodytemperature JamesM.
Ciera...71 AparametricMarkovchaintomodelage-andstate-dependentwear
processes MassimilianoGiorgio,MaurizioGuidaandGianpaoloPulcini...85
CasestudiesinBayesiancomputationusingINLA SaraMartinoandHav ?
ardRue...99 Agraphicalmodelsapproachforcomparinggenesets M.
So?aMassa,MonicaChiognaandChiaraRomualdi...115 VIII Contents
Predictivedensitiesandpredictionlimitsbasedonpredictivelikelihoods
PaoloVidoni...123 Computer-intensiveconditionalinference G.
AlastairYoungandThomasJ. DiCiccio...137
MonteCarlosimulationmethodsforreliabilityestimationandfailure
prognostics EnricoZio...151 ListofContributors
AlessandroBaldiAntognini JamesM. Ciera
DepartmentofStatisticalSciences DepartmentofStatisticalSciences
UniversityofBologna UniversityofPadova Bologna,Italy Padova,Italy
ThomasJ. DiCiccio GrazianoAretusi DepartmentofSocialStatistics
DepartmentofQuantitativeMethods CornellUniversity andEconomicTheory
Ithaca,USA UniversityG. d'Annunzio Chieti-Pescara,Italy
LaraFontanella DepartmentofQuantitativeMethods RaffaeleArgiento
andEconomicTheory CNRIMATI UniversityG. d'Annunzio Milan,Italy
Chieti-Pescara,Italy MassimilianoGiorgio PietroBarbieri
DepartmentofAerospace Uf? cioQualita' andMechanicalEngineering
CernuscosulNaviglio,Italy SecondUniversityofNaples Aversa(CE),Italy
AlessandroBarbiero DepartmentofEconomics Niccolo'Grieco
BusinessandStatistics A. O. NiguardaCa'Granda UniversityofMilan
Milan,Italy Milan,Italy MaurizioGuida MonicaChiogna
DepartmentofElectrical DepartmentofStatisticalSciences
andInformationEngineering UniversityofPadova UniversityofSalerno
Padova,Italy Fisciano(SA),Italy X ListofContributors
AlessandraGuglielmi AntonioPievatolo DepartmentofMathematics
CNRIMATI PolitecnicodiMilano Milan,Italy Milan,Italy
GianpaoloPulcini alsoaf?liatedtoCNRIMATI,Milano IstitutoMotori
NationalResearchCouncil(CNR) FrancescaIeva Naples,Italy
MOX-DepartmentofMathematics PolitecnicodiMilano ChiaraRomualdi
Milan,Italy DepartmentofBiology UniversityofPadova LuigiIppoliti
Padova,Italy DepartmentofQuantitativeMethods andEconomicTheory
H?avardRue UniversityG. d'Annunzio DepartmentofMathematicalSciences
Chieti-Pescara,Italy NorwegianUniversityforScience andTechnology
SaraMartino Trondheim,Norway DepartmentofMathematicalSciences
NorwegianUniversityforScience PiercesareSecchi andTechnology
MOX-DepartmentofMathematics Trondheim,Norway PolitecnicodiMilano
Milan,Italy M. So?aMassa DepartmentofStatisticalSciences
PaoloVidoni UniversityofPadova DepartmentofStatistics Padova,Italy
UniversityofUdine Udine,Italy FulviaMecatti DepartmentofStatistics
G.
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