This volume presents the proceedings of a symposium on the "Control
of the thyroid gland~ regulation of its normal function and
growth," held at the National Insti- tutes of Health, Bethesda,
Maryland on March 20 and 21, 1989. Our motivation for the
organization of this symposium was the fast development in re cent
years of our understan- ding of the regulation of the thyroid - and
the progress in the field of cell regulation in general - which
have led to profound modifications of our view of the control of
the thyroid. Not so many years aga the thyroid was thought to be
controlled by one regulator, the pituitary TSH, which with cyclic
AMP in the role of second messen- ger was considered to express or
regulate most or all processes in the gland. In the last several
years it has been weIl documented that hormones other than TSH and
various growth factors are involved in thyroid growth con- trol and
it has been increasingly clear that several hor- mones and
neurogenic agents are obligate participants in the regulation of
thyroid function. In addition, not only new agonists acting on the
thyroid have been revealed, but new transducer and second messenger
systems have been discovered. In particular the interest has been -
and is- focused on the signals emanating from the hydrolysis of the
inositol phospholipids, comprising the inositol tris-
phosphate/Ca2~ pathway and the diacylglycerol/protein kinase C
pathway.
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Series: |
Advances in Experimental Medicine and Biology, 261 |
Release date: |
June 2013 |
First published: |
1989 |
Authors: |
R. Ekholm
|
Dimensions: |
254 x 178 x 22mm (L x W x T) |
Format: |
Paperback
|
Pages: |
403 |
Edition: |
Softcover reprint of the original 1st ed. 1989 |
ISBN-13: |
978-1-4757-2060-0 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Endocrinology >
Diabetes
|
LSN: |
1-4757-2060-2 |
Barcode: |
9781475720600 |
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