Tumours of the prostate are the commonest types of neoplasm in the
male. Whilst the benign form is virtually a universal condition in
the ageing male, malignant tumours rank amongst the top causes of
cancer death. Despite the fact that the involvement of the testis
in the growth of the prostate has been recognised for almost two
centuries, it was not until the early 1940s that Charles Huggins'
studies on the effect of orchidectomy and oestrogen therapy on
prostatic cancer initiated endocrine manipulation in the management
of this malignancy. During the 1960s progress in the understanding
of the mechanism of hormone action, achieved through advances in
molecular biology and the recognition of certain aspects of
hormonal control in relation to the genome, introduced a new
dimension for approaching endocrine manipulation of prostatic
tumours. By the end of that decade a new scientific discipline
devoted to prostate research had been born, which brought together
investigators in the fields of molecular biology, biochemistry,
endocrinology, immunology, urology and pathology to search for the
cause and to explore methods for advancing the management of
abnormal prostatic growth. Since then a wealth of scientific data
has accumulated on the prostate in which endocrinology has
manifested itself as the cardinal aspect to which most of the
findings can be related.
General
Imprint: |
Springer
|
Country of origin: |
Netherlands |
Release date: |
March 2012 |
First published: |
1983 |
Editors: |
R. Ghanadian
|
Dimensions: |
235 x 155 x 17mm (L x W x T) |
Format: |
Paperback
|
Pages: |
308 |
Edition: |
Softcover reprint of the original 1st ed. 1983 |
ISBN-13: |
978-9401172585 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Endocrinology >
Diabetes
|
LSN: |
9401172587 |
Barcode: |
9789401172585 |
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