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Platelet-Vessel Wall Interactions (Paperback, Softcover reprint of the original 1st ed. 1988)
Loot Price: R2,912
Discovery Miles 29 120
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Platelet-Vessel Wall Interactions (Paperback, Softcover reprint of the original 1st ed. 1988)
Series: The Bloomsbury Series in Clinical Science
Expected to ship within 10 - 15 working days
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The publication of Platelet-Vessel Wall Interactions, the second
monograph in the Bloomsbury Series in Clinical Science, is particu
larly welcome as its appearance signifies the further development
of the Series and its potential for the future. The theme of this
monograph is the pathophysiology of atherosclerosis, a topic that
symbolises the aim of the Series, namely to highlight the important
interfaces between basic medical science and clinical practice. Our
congratulations to the Editors and contributors. London, December
1987 lack Tinker Preface In the Western world, atherosclerosis
causes more illness and death than any other disease. Despite its
devastating effects, the pathogenesis of the disease remains a
matter for hypothesis and con jecture. This monograph owes its
conception to a programme of work directed towards understanding
the basic pathophysiology of atherosclerosis. The circulatory
system is lined by vascular endothelium which has a central role in
maintaining the integrity of the vessel wall and prevent ing
thrombosis. The natural equilibrium existing between normal en
dothelium which supports blood flow, and platelets which serve to
re pair damaged endothelium, is explored in the first two chapters.
Atherosclerosis developing as a response to endothelial injury is
one hypothesis which has stimulated widespread interest, and re
search has largely been directed towards finding the injurious
agent."
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