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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > Allergies
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Auto-immunity in the Endocrine System (Paperback, Softcover reprint of the original 1st ed. 1981)
Loot Price: R2,855
Discovery Miles 28 550
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Auto-immunity in the Endocrine System (Paperback, Softcover reprint of the original 1st ed. 1981)
Series: Monographs on Endocrinology, 20
Expected to ship within 10 - 15 working days
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The present monograph will concern itself with those disorders of
the endocrine system, either associated with destruction,
interference with function or hyper- function, which are considered
to be due to auto-immune processes. Endocrinopathies Non-endocrine
auto-immune disorders associated with the endocrinopathies Graves'
(Basedow's, Parry's) disease Pernicious anaemia Hashimoto's
thyroiditis Vitiligo Idiopathic Addison's disease Myaesthenia
gravis Insulinopenic diabetes mellitus Sjogren's syndrome
Auto-immune oophoritis and orchitis Rheumatoid arthritis
Auto-immune hypoparathyroidism Idiopathic thrombocytopenic purpura
Auto-immune hypophysitis Chronic active hepatitis Possibly some
cases of infertility Primary biliary cirrhosis due to anti-sperm
antibodies Reproduced with permission from Volpe (1977) The above
table indicates those organ-specific endocrinopathies considered to
be due to auto-immune factors, as well as those non-endocrine,
organ-specific auto-immune disorders which may be associated with
them (Volpe 1977). It is evident that such disorders, occurring
without any obvious external cause, raise the very elementary
question of how immune processes directed against self-
constituents could be initiated. Generally, of course, the immune
system acts as a regulatory and defence mechanism, and disorders of
auto-immunity represent breakdowns in this regulatory system. The
following chapters will be concerned with the individual components
ofthe endocrine system so affected by auto-immune processes; it
will first be necessary to provide an initial chapter for the
purpose of summarizing some general principles of immunology, in
order to place the immune disorders of the endocrine system in
context.
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