There are many plants in Kashmir valley which have been shown to
possess medicinal properties. Among them is Euphorbia helioscopia
which is known for its medicinal values. At present drug resistance
is a worldwide problem and much emphasis is being laid on the
natural plant sources to act as antibiotics which can overcome this
problem. Euphorbia helioscopia which is known for its medicinal
values has febrifuge and vermifuge activities in its roots and stem
respectively. The root is anti helminthic. The milky sap is applied
externally to skin eruptions. The seeds, mixed with roasted pepper,
have been used in the treatment of cholera and the oil from the
seeds has purgative properties. However, isolation of any
antibacterial protein has not been reported till date. The essence
of the work was to check the antibacterial activity of the plant
following its purification and characterization from leaves using
conventional protein purification techniques. The lectin is a
homodimer (Mr 65000Da), thermostable between 0 C- 40 C but exhibits
a narrow range of pH stability being optimally active at pH 7. The
lectin shows antimicrobial activity against P. aeruginosa,
K.pneumoniae and E. coli.
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