Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and
Innovative Reversal Strategies brings current knowledge from an
international team of experts on the science and clinical
management of glioblastoma chemoresistance. The book discusses
topics such as molecular mechanisms of chemoresistance,
experimental models to study chemoresistance, chemoresistance to
drugs other than Temozolomide, and specific strategies to reverse
chemoresistance. Additionally, it encompasses information on how to
mitigate chemoresistance by targeted enhancement of p53 function.
This book is a valuable resource for cancer researchers,
oncologists, neuro-oncologists and other members of the biomedical
field. Glioblastoma (GBM) is the most invasive and malignant
primary brain tumor in humans with poor survival after diagnosis,
therefore it is imperative that molecular and cellular mechanisms
behind therapy resistant GBM cells, as well as the therapeutic
strategies available to counter the resistance are comprehensively
understood.
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