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Tamoxifen Concepts & Cancer - New Paradigms (Hardcover)
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Tamoxifen Concepts & Cancer - New Paradigms (Hardcover)
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Tamoxifen was first approved in 1977 and up to now remains a
noteworthy therapeutic weapon to treat mainly breast cancer.
However, further considerations exist regarding the tamoxifen
profile. This book discusses recent research and future
perspectives in the tamoxifen field. The topics discussed include
tamoxifen pharmacokinetics, pharmacodynamics, adverse effects,
clinical indications, therapeutic drug monitoring, autophagy
mechanisms, tamoxifen topical formulation and breast cancer risk
prevention, the use of tamoxifen in an oestrogen-independent manner
for various neoplasms (Hepatocellular carcinoma, renal cell
carcinoma, high grade glioma), mechanisms of resistance, potential
role of CYP2D6, tamoxifen and antidepressants interaction in a
psychiatric view, obesity influence in tamoxifen treatment,
electrical pulse-mediated tamoxifen delivery, and tamoxifen in
melanoma treatment.
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