Human Longevity - Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution (Hardcover)

More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman's famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging. Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membrane oxidation introduced in this book. This concept is consistent with recent discoveries showing that mitochondria-targeted antioxidants prevent Huntington's disease, Parkinson's disease, and traumatic brain disease in animal models of neurodegeneration. This book explores a unified theory of aging based on bioenergetics. It covers a variety of topics including an introduction to the science of human aging, the Darwinian selection of membranes enabling longevity, a revised mitochondrial membrane hypothesis of aging, and various mechanisms that protect human mitochondrial membranes, thereby enabling longevity.

General

Imprint:	Crc Press
Country of origin:	United States
Release date:	September 2014
First published:	2014
Authors:	Raymond C. Valentine • David L. Valentine
Dimensions:	234 x 156 x 19mm (L x W x T)
Format:	Hardcover
Pages:	259
ISBN-13:	978-1-4665-9486-9
Categories:	Books > Science & Mathematics > Biology, life sciences > Molecular biology Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > Cellular physiology Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	1-4665-9486-1
Barcode:	9781466594869

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