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Neurons and the DHA Principle (Paperback)
Loot Price: R1,838
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Neurons and the DHA Principle (Paperback)
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Studies with bacteria and other systems suggest that the omega-3
fatty acid DHA confers great benefits to neurons in maximizing both
speed of neural impulses and energy efficiency. Unfortunately,
studies also show that DHA's ease of oxidation damages membrane
integrity. Exploring this duality, Neurons and the DHA Principle
proposes a new model for the causes of neurodegeneration, in which
DHA-enriched membranes of neurons become dysfunctional and
energetically wasteful, triggering the premature death of neurons.
The challenge of this book is to digest how DHA acts as an
essential building block of neurons while also conspiring for their
assassination during aging. As the book reviews the extraordinary
properties of DHA in life forms from deep-sea bacteria to human
neurons, it asks: Is there a trade-off between speed and efficiency
of brain function enabled by DHA versus longevity or life span? Has
modern medicine advanced significantly in the treatment of the body
but not necessarily of the brain? What are the molecular
explanations for the decline in brain health during the age of
longevity? A full accounting of the roles of DHA in neurons
requires balancing the enormous benefits of these molecules against
the risks. Introducing the dual chemical personalities of DHA from
an evolutionary perspective, Neurons and the DHA Principle explores
DHA from the standpoint of benefit-risk analysis, opening new
perspectives for understanding how DHA functions in neurons.
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