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Nerve Sheath Tumors - Signs, Symptoms and Treatment (Paperback)
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Nerve Sheath Tumors - Signs, Symptoms and Treatment (Paperback)
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There are a variety of tumors that can arise from various
compartments and cellular components of peripheral nerves
throughout the body. These peripheral nerve sheath tumors run the
gamut from benign, fairly commonly encountered neoplasms such as
schwannomas and neurofibromas to rarer, low grade neoplasms and
variants such as perineuriomas, mucosal neuromas, palisaded
encapsulated neuromas, granular cell tumors and nerve sheath
myxomas to malignant neoplasms, so-called malignant peripheral
nerve sheath tumors. They are generally classified as soft tissue
neoplasms but they differ from most other tumors in this general
grouping in a number of ways. Many of them are associated with
genetic disorders or hereditary tumor syndromes and the majority of
malignant peripheral nerve sheath tumors arise from a benign
precursor tumor, neurofibroma. Their precise diagnosis and
classification necessitates careful correlation with clinical and
surgical data along with attention to histologic and
immunohistochemical features. This text is comprised of a
collection of chapters reviewing some of the myriad aspects of this
group of neoplasms and includes discussions of the epithelioid
variant of malignant peripheral nerve sheaths, peineuriomas arising
in the colon, peripheral nerve sheath tumors arising in the oral
cavity, jaw and salivary gland regions of the head and neck, and
the melanotic variant of schwannoma.
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