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Books > Professional & Technical > Biochemical engineering
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Biofabrication of 3D Liver Tissue Constructs as Drug Metabolism Models (Paperback)
Loot Price: R1,572
Discovery Miles 15 720
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Biofabrication of 3D Liver Tissue Constructs as Drug Metabolism Models (Paperback)
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Coincident with the convergence of a unique layered solid freeform
fabrication (SFF) technologies along with microfabrication
techniques, a three-dimensional bioprinted micro-organ can serve as
an in vitro platform for cell culture, drug screening, or to elicit
further biological insights, particularly for NASA's interest of a
flight-suitable high-fidelity microscale platform to study drug
metabolism in space and planetary environments. This book details
the principles, methodology, and engineering science basis that
undergird the direct cell writing fabrication process development
and adaptation of microfluidic devices for the creation of a in
vivo simulating drug screening model. This model involves the
combinatorial setup of an automated syringe- based, layered direct
cell writing bioprinting process with soft lithographic
micro-patterning techniques to fabricate a microscale in vitro
device housing a chamber of bioprinted three-dimensional microorgan
that biomimics the cell's natural microenvironment for enhanced
performance and functionality.
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