Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Cancer Diagnostics - Current and Future Trends (Hardcover, 2004 ed.)
Loot Price: R5,591
Discovery Miles 55 910
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Cancer Diagnostics - Current and Future Trends (Hardcover, 2004 ed.)
Series: Contemporary Cancer Research
Expected to ship within 10 - 15 working days
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In the past, many tumor marker laboratory tests have not been
sensitive enough for the very early detection of cancer. However,
many of them have nonetheless proved useful in monitoring therapy,
following the course of the tumor, and predicting prog- nosis.
Today, cancer may be viewed as a genetic disease with various
specific chromo- somal and nucleotide aberrations, such as
mutations, deletions, gene amplification, gene rearrangements, and
translocations occurring during the transformation of a nor- mal
cell into a malignant cell. The considerable advances in technology
during the past several years have greatly enhanced our ability to
detect human cancers in the very early stages of tumor forma- tion.
These technologies include: (1) nucleotide molecular assays
(genomics); (2) proteomics (multiplex protein measurements); (3)
DNA microarrays; and (4) bio- informatics. Many of these
technologies are already helping in the integration and use of
multiple biomarkers for tumors. Although the individual biomarkers
may reveal only limited information, the use of multiple biomarkers
can help markedly elevate the diagnostic capabilities for early
detection of tumors.
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