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Drug Disposition and Pharmacokinetics - Principles and Applications for Medicine, Toxicology and Biotechnology 2e (Hardcover)
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Drug Disposition and Pharmacokinetics - Principles and Applications for Medicine, Toxicology and Biotechnology 2e (Hardcover)
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Drug Disposition and Pharmacokinetics The most up-to-date edition
of a leading reference in drug disposition and pharmacokinetics In
this new, fully-revised edition of Drug Disposition and
Pharmacokinetics: Principles and Applications for Medicine,
Toxicology and Biotechnology the authors deliver an authoritative
and comprehensive discussion of the fate of drug molecules in the
body, as well as its implications for pharmacological and clinical
effects. The text offers a unique and balanced approach that
combines discussion of the specific physical and biological factors
affecting the absorption, distribution, metabolism, and excretion
of drugs, with mathematical assessments of plasma and body fluid
concentrations. The book assumes little prior knowledge and is an
ideal reference for practicing professionals in industry as well as
researchers and academics. This latest edition provides readers
with a new introductory chapter, as well as new chapters covering
monoclonal antibodies, the role of stereochemistry in drug
disposition and pharmacokinetics, DMPK in non-human species, and
the recent use of AI in drug development. Readers will also find:
Thorough introductions to drug disposition, pharmacokinetics, and
pharmacokinetic modeling In-depth treatments of the kinetics of
drug elimination and the relationship between concentration and
effect, including PK-PD modeling Comprehensive discussions of
predictive pharmacokinetics and the disposition of biological
molecules, including peptides and monoclonal antibodies Detailed
examinations of the effects of sex, pregnancy, age, and disease, as
well as drug monitoring in therapeutics and the use of AI in drug
development and treatment Perfect for professionals and researchers
working with the scientific aspects of drug disposition in human
and veterinary medicine, toxicology, and pharmacology. Drug
Disposition and Pharmacokinetics will earn a place in the libraries
of students of senior-level courses in pharmacy.
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