Diabetes is now one of the major causes of morbidity worldwide. In
many cases, the onset of diabetes is progressive, developing via a
condition of insulin resistance. This book considers the
development of this condition, its consequences and clinical and
therapeutic aspects.
The book reviews the normal biology of insulin action on glucose,
lipids and proteins. It considers the pathological basis for
insulin resistance in animal models and humans, and discusses the
influence of heredity, dietary factors and exercise. Clinical
consequences including dyslipidaemia, hypertension and polycystic
ovary syndrome, and therapeutic strategies for treatment are also
examined.
* Provides an expert review of the phenomenon of insulin
resistance
* Brings together a host of recent research for the first
time
* Written by leading experts in biological and clinical research
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