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Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
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Epigenetic Mechanisms in Cancer, Volume 3 (Hardcover)
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Epigenetic Mechanisms in Cancer, Volume 3 (Hardcover)
Series: Translational Epigenetics
Expected to ship within 10 - 15 working days
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Epigenetic Mechanisms in Cancer provides a comprehensive analysis
of epigenetic signatures that govern disease development,
progression and metastasis. Epigenetic signatures dictating tumor
etiologies present an opportunity for biomarker identification
which has broad potential for improving diagnosis, prognosis,
prediction, and risk assessment. This volumes offers a unique
evaluation of signature differences in childhood, sex-specific and
race-specific cancers, and in doing so broadly illuminates the
scope of epigenetic biomarkers in clinical environments. Chapters
detail the major epigenetic process in humans consisting of DNA
methylation, histone modifications and microRNAs (miRNAs) involved
in the initiation, progression and metastasis of tumors. Also
delineated are recent technologies such as next generation
sequencing that are used to identify epigenetic profiles (primarily
methylation analysis) in samples (normal, benign and cancerous) and
which are highly important to the analysis of epigenetic outcomes.
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