Enteropathogenic Escherichia coli (EPEC) strains are diarrheagenic
E. coli belonging to specific serotypes, historically associated
with outbreaks of infantile diarrhea, which are one of the main
causes of severe diarrhea throughout the world. Several chromosomal
and plasmid-borne virulence factors have been linked with the
ability of certain strains to cause diarrhea. Over the last few
years, numerous outbreaks of infections with strains producing
extended spectrum -lactamases (ESBLs) and AmpC -lactamases, has
been observed worldwide. In Iraq, few reports are available on the
prevalence and molecular identification of EPEC. In addition,
little attention has been paid to the molecular studies of ESBLs
and AmpC -lactamases. Therefore, there is an increase demand to
investigate the role of EPEC in children with diarrhea and identify
the prevalence of -lactam resistance among these strains. This book
provides a new data on the prevalence of EPEC in children younger
than two years of age in Iraqi hospitals as well as characterizes
their virulence genes and detection the genetic factors controlling
production of ESBLs and AmpC -lactamases.
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