This book bridges the gap between advances in basic biology and
chemistry and technological applications in the field of toxicity
assessments. It describes areas of progress in the laboratory and
clinic and discusses aspects of cellular organelles. It also covers
the basic principles and applications of modern toxicological tools
such as transcriptomic, proteomic, and metabolomic approaches. The
recent developments on molecular modeling and systems biology are
described with an eye on the future establishment of virtual cell
technology. Finally the clinical implications for the understanding
of acute and chronic renal toxicity are studied.
General
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