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Base Editors - Methods and Protocols (Hardcover, 1st ed. 2023)
Loot Price: R5,765
Discovery Miles 57 650
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Base Editors - Methods and Protocols (Hardcover, 1st ed. 2023)
Series: Methods in Molecular Biology, 2606
Expected to ship within 10 - 15 working days
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This volume explores base editors (BEs), an invaluable CRISPR-based
genome editing tool with a wide variety of versatile applications.
Beginning with an overview of BEs, their diverse variants, and
computational tools, the book continues with experimental
applications of BEs for disease modeling in mammalian cells and
generating mutagenic mice, therapeutic base editing strategies,
which covers delivery methods of BE-encoded DNA plasmids, mRNAs, or
ribonucleoproteins through viruses or non-viral lipid
nanoparticles, and lastly, the use of BEs in plants and bacteria.
Written for the highly successful Methods in Molecular Biology
series, chapters include introductions to their respective topics,
lists of the necessary materials and reagents, step-by-step and
readily reproducible laboratory protocols, and tips on
troubleshooting and avoiding known pitfalls. Authoritative and
practical, Base Editors: Methods and Protocols serves as an ideal
guide for researchers looking to use base editors to continue their
studies in an array of fields.
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