Today, cells are commonly analyzed en masse, with thousands of
cells per sample, yielding results on the average response of the
cells. However, cellular heterogeneity implies that in order to
learn more about cellular behaviour, it is important to study how
individual cells respond, one by one. In Single-Cell Analysis:
Methods and Protocols, experts in the field provide an update on
the field of single-cell analysis wherein the latest findings and
applications are described in detail. The methods described in this
book include a few examples of conventional methods and several
examples of miniaturized methods. Written in the highly successful
Methods in Molecular Biology (TM) series format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and key tips on troubleshooting and avoiding
known pitfalls. Authoritative and accessible, Single-Cell Analysis:
Methods and Protocols encourages readers to explore new ways of
studying cells that may help lead to exciting new discoveries.
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