"Galectins: Methods and Protocols "is the first book solely
dedicated to methodological approaches designed to study galectin
function. The galectin family represents one of the most
pleiotropic families, with individual members having been
implicated in various aspects of nearly every biological process
described, from RNA splicing to complex regulatory circuits that
orchestrate adaptive immunity. Given the diverse roles of galectins
in a variety of biological systems, studying these glycan binding
proteins often requires the assimilation of diverse technical
skills to fully appreciate their biological function. Their nearly
ubiquitous expression and ability to bind highly modifiable
carbohydrate ligands, in addition to a variety of other regulatory
proteins, allows these glycan binding proteins (GBPs) to possess
the capacity to regulate a wide variety of biological processes.
Individual chapters are dedicated to examining salient features of
galectin functions. Written in the successful "Methods in Molecular
Biology" series format, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible protocols, and notes on
troubleshooting and avoiding known pitfalls.
Authoritative and easily accessible, "Galectins: Methods and
Protocols "seeks to serve both professionals and novices with a
useful framework when examining galectin function for many years to
come."
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