This book is the first to summarize the current knowledge of the
cell biology of lens epithelial cells in relation to and in the
development of posterior capsular opacification (PCO). PCO remains
the most common long-term complication of modern cataract surgery,
occurring months or years after cataract surgery, unlike most other
complications that tend to arise during or soon after the
procedure. Opacification of the posterior capsule appears to be
linked to lens epithelial cells that are left behind in the eye
during cataract removal. These cells proliferate, migrate across
the posterior lens capsule, and undergo changes that result in
fibrous or pearl-type opacities in the capsule.
The first section of the text explains the molecular mechanism
and biology of lens epithelial cells that lead to the incidence of
PCO. In the second part, in addition to a description of the
mechanism and pathological condition of PCO, surgical methods and
devices for preventing PCO are discussed in detail." ""Lens
Epithelium and Capsular Opacification" will benefit not only young
clinical residents and junior researchers, but also established
faculty in the clinical or basic academic field.
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