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Books > Medicine > Clinical & internal medicine > Geriatric medicine
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Cell and Animal Models in Aging and Dementia Research (Paperback, illustrated edition)
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Cell and Animal Models in Aging and Dementia Research (Paperback, illustrated edition)
Series: Journal of Neural Transmission. Supplementa, 44
Expected to ship within 10 - 15 working days
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Although age has been recognized as a risk factor for late-onset
dementia of Alzheimer type, its etiology is unknown as yet. Several
age-related metabolic abnormalities may thus become important for
the pathogenesis of the late-onset form. Studies at the
cellular/molecular level in brain tissue are possible post mortem,
but lack information on the beginning of the disorder. In this
supplement, different approaches are dealt with how to induce
structural and/or metabolic abnormalities in relevant cell
cultures, in brain slices and in experimental animals, and how
behavioral changes parallel the metabolic variations.
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