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Proteome Bioinformatics (Hardcover, 2010 ed.)
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Proteome Bioinformatics (Hardcover, 2010 ed.)
Series: Methods in Molecular Biology, 604
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The feld of proteomics moves rapidly. New methods, techniques,
applications, standards, models and software appear almost on a
daily basis. Accompanying this are plenty of texts on the
experimental side of the feld and a few appearing on the informatic
and data analysis side. This latterly includes one in the Methods
in Molecular Biology series tackling the specifc analysis of "Mass
spectrometry data in proteomics" in MMB vol. 376. This current
collection builds on this, but takes a broader view of proteome
data analysis covering data analysis essentials, but also the
databases and data models, as well as practical consid- ations for
analysing database search results, annotating genomes, and speeding
up searches. It also digs deeper into some topics, such as decoy
database searching and aspects of signal processing in proteomic
mass spectrometry. The aim of the volume is to provide the reader
with a mix of reviews and methodology chapters, which build from
the essentials of database searching in proteomics, on through
specifc data processing challenges to databases, data standards and
data models.
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