Sentinel lymph node (SLN) procedures have opened a window of
opportunity for the study of micrometastasis. In eighty percent
(80%) of metastasis there lies an orderly pattern of progression
via the lymphatic network, while 20% of the time systemic
metastasis occurs, bypassing the lymphatic system. During the past
two decades, significant progress has been achieved in
understanding the anatomical, functional, cellular and molecular
aspects of the lymphovascular system and the metastasis process.
A- Molecular imaging advances help to localize early cancers
more precisely.
A- Current status of the immune responses in the draining lymph
nodes against cancer is summarized.
A- New paradigms of early cancer growth, proliferation,
overcoming apoptosis are exploited in the development of anticancer
treatment.
In this book, basic scientists and clinicians exchange ideas so
that laboratory findings can be applied to clinical dilemmas, and
clinical problems can be targeted for research in the
laboratory.
General
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