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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2 (Hardcover, 1996 ed.)
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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2 (Hardcover, 1996 ed.)
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The 7th International Symposium on Platinum and other metal
coordination compounds in Cancer Chemotherapy, ISPCC '95, organized
by the European Cancer Centre, was held in Amsterdam, the
Netherlands, March 1-4, 1995. As with previous ISPCC meetings, the
goal of ISPCC '95 was to bring together c1inicians, clinical
investigators, scientists, and laboratory workers from many
disciplines to promote further collaboration and cooperation in the
development of new platinum and other metal coordination compounds
as weil as in new ways to use 'c1assical' drugs as cisplatin and
carboplatin in the treatment of cancer. Important aspects addressed
by experts in the field inc1uded the synthesis and activity of new
platinum compounds, the biochemistry and molecular pharrnacology as
weil as the c1inical pharrnacology of this c1ass of antineoplastic
agents, an overview of current c1inical studies, one special
minisymposium on the mechanisms of cell kill of platinum, and one
on resistance against platinum compounds. Finally, the current
status of development of nonplatinum metal complexes was discussed.
This volume contains the contributions of the various speakers at
ISPCC '95 and provides an up-to-date and comprehensive overview of
this important c1ass of anticancer agents, ranging from synthesis
and molecular pharrnacology on one hand to c1inical pharrnacology
and cIinical investigations on the other hand. The Organizing
Corrunittee and Editors wish to express their gratitude to the
contributors to this volume, to the various organizations and
pharrnaceutical companies for their generous sponsoring of ISPCC
'95, and to the Plenum Publishing Company for their help in
producing this volume.
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