This timely volume brings together the latest basic and clinical
insights on the cellular and mediator mechanisms involved in the
induction and persistence of airway dysfunction of asthma by over
90 experts in the field-paving the way for developing novel and
more effective antiinflammatory therapeutic agents and strategies.
Furnishing a comprehensive and up-to-date view of the expanding and
interrelated components underlying asthma pathogenesis,
Inflammatory Mechanisms in Asthma
describes how evidence on airway inflammation is obtained with
invasive and noninvasive procedures, such as bronchoalveolar lavage
and sputum analysis
reviews the complex interactions of inflammatory cells that
contribute to chronic inflammation and bronchial hyperreactivity,
including eosinophils, basophils, neutrophils, fibroblasts,
epithelial cells, and macrophages
considers mast cells, cytokines, neural factors, leukotrienes,
kinins, and other mediators that regulate the development,
establishment, or resolution of asthma exacerbations
presents new information suggesting that airway changes in asthma
can lead to remodeling or airway fibrosis
and more
Enhanced with over 4700 references, tables, drawings, and
photographs, this compelling investigation into the pathophysiology
of asthma is an indispensable resource for pulmonologists,
physiologists, immunologists, allergists, epidemiologists,
biochemists, molecular biologists, and graduate and medical school
students in these disciplines.
General
Imprint: |
Routledge Member of the Taylor and Francis Group
|
Country of origin: |
United States |
Series: |
Lung Biology in Health and Disease |
Release date: |
May 1998 |
First published: |
1998 |
Editors: |
Stephen Holgate
|
Dimensions: |
234 x 156 x 54mm (L x W x T) |
Format: |
Hardcover
|
Pages: |
1090 |
ISBN-13: |
978-0-8247-0122-2 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Respiratory medicine
Promotions
|
LSN: |
0-8247-0122-4 |
Barcode: |
9780824701222 |
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