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Drug-Induced Valvular Heart Disease (Paperback, New)
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Drug-Induced Valvular Heart Disease (Paperback, New)
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The notion that drugs can induce valvular heart disease (VHD) has
occurred since the sixties and has received a lot of attention in
recent years. Overstimulation of the serotonin 2B receptor (5-HT2B)
leads to valvular fibroblast proliferation and thickening of the
valvular leaflets with reduced mobility and regurgitation as a
consequence. This book focuses on different aspects of this
distinct kind of valvulopathy including pathophysiology of
drug-induced VHD, histopathological and echocardiographic
characteristics,drugs associated with VHD, the influence of
cumulative drug dose and risk factors and others.
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