Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Monoclonal Antibodies in Cancer (Hardcover, 1985 ed.)
Loot Price: R3,047
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Monoclonal Antibodies in Cancer (Hardcover, 1985 ed.)
Series: Contemporary Biomedicine, 6
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This represents the third volume in a series on cancer markers pub-
lished by the Humana Press. The first volume, published in 1980,
stressed the relationship of development and cancer as reflected in
the production of markers by cancer that are also produced by
normal cells during fetal development. The concept that cancer
represents a problem of differentiation was introduced by Barry
Pierce in describing differenti- ation of teratocarcinomas.
Highlighted were lymphocyte markers, alphafetoprotein,
carcinoembryonic antigen, ectopic hormones, enzymes and isozymes,
pregnancy proteins, and fibronectin. The second volume, published
in 1982 and coedited with Britta Wahren, focused on the diagnostic
use of oncological markers in human cancers, which were
systematically treated on an organ by organ basis. At that time,
the application of monoclonal antibodies to the identification of
cancer markers was still in a very preliminary stage. A general
introduc- tion to monoclonal antibodies to human tumor antigens was
given there by William Raschke, and other authors included coverage
of those mark- ers then detectable by monoclonal antibodies in
their chapters.
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