Autoimmune Reactions tackles fundamental questions about how the
immune system can destroy invading microbial pathogens without
causing damage to itself and other "self" systems. The
authoritative experts writing here explore the mechanistic aspects
of such autoimmune diseases as lupus, rheumatoid arthritis,
diabetes, and autoimmune thyroid disease, and where possible
delineate how malfunctioning immunological mechanisms can lead to
clinical symptoms. They also discusses possible general mechanisms
of autoimmune disease-e.g., molecular mimicry and dysfunctional
antigen presentation-and their current limitations as unifying
explanations of the diseases described. The book illustrates the
type of thinking and research that should eventually permit
development of palliatives and cures for autoimmune diseases.
General
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