This handbook on vacuolar and plasma membrane H+-ATPases is the
first to focus on an essential link between vacuolar H+-ATPase and
the glycolysis metabolic pathway to understand the mechanism of
diabetes and the metabolism of cancer cells. It presents recent
findings on the structure and function of vacuolar H+-ATPase in
glucose promoting assembly and signaling, in addition to describing
the regulatory mechanisms of vacuolar H+-ATPase in yeast cells,
neural stem cells, kidney cells, cancer cells, as well as under
diabetic conditions.
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