Calcitonin Gene-Related Peptide (CGRP) Mechanisms - Focus on Migraine (Paperback, 1st ed. 2019)

This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine. The various chapters address the origin, localization and function of CGRP and its receptor in the peripheral nervous system, in the cardiovascular system, and in other tissues and organs. Further attention is paid to the drug discovery pathway where recent findings show the beneficial effect of small molecule antagonists of the CGRP receptors for the relief of the migraine attack and of monoclonal antibodies against CGRP or the CGRP receptor for migraine prevention.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Handbook of Experimental Pharmacology, 255
Release date:	September 2020
First published:	2019
Editors:	Susan D. Brain • Pierangelo Geppetti
Dimensions:	235 x 155mm (L x W)
Format:	Paperback
Pages:	192
Edition:	1st ed. 2019
ISBN-13:	978-3-03-021456-2
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology Books > Medicine > Other branches of medicine > Anaesthetics > Pain & pain management Books > Medicine > Other branches of medicine > Pharmacology > General Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
LSN:	3-03-021456-7
Barcode:	9783030214562

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