0
Your cart

Your cart is empty

Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology

Buy Now

Bone Toxicology (Paperback, Softcover reprint of the original 1st ed. 2017) Loot Price: R5,142
Discovery Miles 51 420
Bone Toxicology (Paperback, Softcover reprint of the original 1st ed. 2017): Susan Y. Smith, Aurore Varela, Rana Samadfam

Bone Toxicology (Paperback, Softcover reprint of the original 1st ed. 2017)

Susan Y. Smith, Aurore Varela, Rana Samadfam

Series: Molecular and Integrative Toxicology

 (sign in to rate)
Loot Price R5,142 Discovery Miles 51 420 | Repayment Terms: R482 pm x 12*

Bookmark and Share

Expected to ship within 10 - 15 working days

The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments. The book is divided into three parts. The first part describes our current understanding of bone biology and its primary regulatory pathways. Additional chapters address regulatory and study design considerations for incorporating bone end points in toxicology studies, with special consideration being given to juvenile toxicology studies. This is intended to address recent regulatory requirements to evaluate skeletal development for drugs in development for pediatric populations. The second part of the book describes the principal techniques and methods used in bone research; understanding how these end-points are derived is fundamental to their appropriate application. These first two parts of the book provide the background and the means to develop the concepts in part three which describes bone and its interaction with other organ systems. The unique series of chapters in part three, contributed to by key leaders in their respective fields and in bone research, provides a comprehensive collective work. Although constantly evolving, the crosstalk and interaction of the skeleton with several organ systems is now recognized and well documented, such as for the reproductive system, muscle and kidney, while our understanding of the interaction with other organ systems, such as the immune system and CNS, is in its infancy. Recent work highlights the key role of the skeleton in the regulation of energy metabolism and the impact this has on research in metabolic diseases such as obesity and diabetes. The hope is that this book will enlighten many and encourage more to explore the impact of new compounds on the skeleton in the development of effective and safe drugs.

General

Imprint: Springer International Publishing AG
Country of origin: Switzerland
Series: Molecular and Integrative Toxicology
Release date: June 2018
First published: 2017
Editors: Susan Y. Smith • Aurore Varela • Rana Samadfam
Dimensions: 235 x 155 x 25mm (L x W x T)
Format: Paperback
Pages: 474
Edition: Softcover reprint of the original 1st ed. 2017
ISBN-13: 978-3-319-85848-7
Categories: Books > Medicine > Other branches of medicine > Pharmacology > General
Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > Animal pathology & diseases
Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
Promotions
LSN: 3-319-85848-3
Barcode: 9783319858487

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!

You might also like..

Intelligent Materials for Controlled…
Steven M Dinh, John DeNuzzio, … Hardcover R2,375 Discovery Miles 23 750
The Biochemistry of Drug Metabolism…
B. Testa Paperback R2,344 R1,920 Discovery Miles 19 200
An Introduction to Creating Standardized…
Todd Case, Yuting Tian Hardcover R1,623 Discovery Miles 16 230
Vaccine Development - From Concept to…
A. Krishna Prasad Hardcover R5,315 Discovery Miles 53 150
Magnesium in Human Health and Disease
Sara Castiglioni, Giovanna Farruggia, … Hardcover R2,335 R1,985 Discovery Miles 19 850
Industrial Pharmacy
Ajay Semalty Hardcover R1,739 Discovery Miles 17 390
Bioequivalence study of Drug - Its…
Bhaswati Pal, Shubhasis Dan, … Hardcover R1,009 Discovery Miles 10 090
Pharmaceutical Engineering
Dulal Krishna Tripathi, Nirmalya Tripathi Hardcover R1,668 Discovery Miles 16 680
Pharmaceutics - Basic Principles and…
Dulal Krishna Tripathi Hardcover R1,571 Discovery Miles 15 710
Guidelines and Screening Methods of…
Surendra H Bodakhe, Parag Jain, … Hardcover R1,518 R1,314 Discovery Miles 13 140
Studies in Natural Products Chemistry…
Atta-ur Rahman Hardcover R8,332 Discovery Miles 83 320
Multifunctional Nanocarriers for…
Md. Abul Barkat, Harshita A.B., … Hardcover R7,127 Discovery Miles 71 270

See more

Partners