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Gallopamil - Pharmacological and Clinical Profile of a Calcium Antagonist (German, Paperback)
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Gallopamil - Pharmacological and Clinical Profile of a Calcium Antagonist (German, Paperback)
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Sinee the introduetion of Gallopamil in 1983 this drug has been
applied in similar indications as Verapamil. Predominantly pat-
ients with stable or unstable angina peetoris, with hypertension,
and hypertrophie eardiomyopathy have been treated. As far as ean be
judged from preliminary clinieal experienee Gallopamil aehieves
similar results as Verapamil with mueh lower doses. Instead of 3
times 160 mg Verapamil 2 to 3 times 50 mg Gallopamil ean be
applied. Although the speetrum of side effects ofboth drugs is
similar it is evident that oeeasionally patients ean tolerate one
better than the other. Complaints about eonstipation may be less
frequent with Gallopamil whereas stomaeh trouble may be more
frequent. Frankfurt, August 1984 M. KALTENBACH R. HOPF v Table of
Contents Gallopamil (D 600) - a Calcium Antagonist of High Potency
and Specificity. Effects on the Myocardium and Pacemakers (A.
FLECKENSTEIN, B. FLECKENSTEIN, F. SPAEH and Y. K. BYON). . . . . .
. . . . . . . . . . . . . . . . . . 1 2 Blockade ofthe Ca +
-dependent Bioelectrical Automaticity and Electromechanical
Coupling of Smooth Musc1e Cells by Gallopamil (D 600) (G.
FLECKENSTEIN-GRUEN and A. FLECKENS TEIN) . . . . . . . . . . . . .
. . . . . . . . . . 33 Studies on the Mechanism of Action of D 600
on Isolated Myocytes (W. TRAUTWEIN and J. HESCHELER) . . . . . . .
49 Studies In Vitra and In Vivo on the Effect of Gallopamil on
Coranary Vessels (A. G. B. Kov ACH, L. LIGETI, M. BAKOS, G. RUBANYI
and A. KOLLER) . . . . . . . . . . . . . . . . . . 58
Electraphysiological Studies with Gallopamil on the Myocardium
ofthe Human Ventric1e (H. NAWRATH and XIAN-GANG ZONG) . . . . . . .
. . . . . . . . . . . . . . . .
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