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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical)
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Chromatin and Disease (Hardcover, 2007 ed.)
Loot Price: R5,864
Discovery Miles 58 640
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Chromatin and Disease (Hardcover, 2007 ed.)
Series: Subcellular Biochemistry, 41
Expected to ship within 10 - 15 working days
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The packaging of genomic DNA together with core histones, linker
histones, and other functional proteins into chromatin play key
roles in nuclear processes such as transcription, replication,
repair and recombination. Research in the last two decades has
unveiled the fact that many diseases involve an aberration of these
processes at the chromatin level. Similarly, it is becoming clear
that different processes such as chromatin assembly, remodeling of
chromatin structure coupled to covalent modification of histone and
non-histone proteins, chromatin modifying enzymes and last but not
the least, important DNA-templated phenomena are the potential drug
targets for diseases such as different types of cancer,
neurodegenerrative diseases, AIDS etc.
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