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Pharmacology in Drug Discovery - Understanding Drug Response (Paperback)
Loot Price: R1,554
Discovery Miles 15 540
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Pharmacology in Drug Discovery - Understanding Drug Response (Paperback)
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Total price: R1,574
Discovery Miles: 15 740
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Pharmacology in Drug Discovery: Understanding Drug Response is
designed for all students, recent graduates, and new researchers in
the pharmaceutical and biotechnology industries who need to
interpret change in physiology induced by a chemical substance.
Physiological systems customize chemical signal input to their own
needs; therefore the same drug can have different effects in
different physiological systems. The field of pharmacology is
unique in that it furnishes the tools to analyze these different
behaviors and traces them to their root cause. This enables
predictions of drug behavior to be made in all systems, an
invaluable tool for drug discovery because almost all drugs are
developed in test systems far removed from the therapeutic one.
This valuable resource provides simple explanations of the ways in
which biological systems use basic biochemical mechanisms to
produce fine chemical control of physiology, allowing for more
informed predictions of drug effects in all systems and forming the
basis of the drug-discovery process. Chapters follow a logical
progression on how to characterize the pharmacology of any given
molecule, and include important terminology, chapter summaries,
references, and review questions to aid the reader in understanding
and retention of the material.
Enables the reader to interpret drug dose-response data and make
mechanistic inferences at the molecular levelBridges the gap
between biochemistry and therapeutic medicineChapters include key
topics such as drug affinity and efficacy, enzymes as drug targets,
in vivo pharmacology, safety pharmacology, and more"
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