This book summarizes the latest findings about the role of cancer
stem cells (CSCs) in cancer biology and how this knowledge could be
used for novel anticancer therapies. It provides an overview of
CSCs in selected malignancies with particular emphasis on
hematopoietic neoplasias. It then reviews the role of CSCs in
metastasis formation and initiation of cancer relapses. It also
examines the dark site of cancer therapy such as conventional
cancer therapies that may lead to the origin of recurrence CSCs.
Finally, it supplies a brief overview of current concepts that may
allow for a selective eradication of CSCs.
General
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