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Antibiotic Discovery and Development (Hardcover, 2012)
Loot Price: R8,911
Discovery Miles 89 110
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Antibiotic Discovery and Development (Hardcover, 2012)
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This volume covers all aspects of the antibiotic discovery and
development process through Phase II/III. The contributors, a group
of highly experienced individuals in both academics and industry,
include chapters on the need for new antibiotic compounds,
strategies for screening for new antibiotics, sources of novel
synthetic and natural antibiotics, discovery phases of lead
development and optimization, and candidate compound nominations
into development. Beyond discovery , the handbook will cover all of
the studies to prepare for IND submission: Phase I (safety and dose
ranging), progression to Phase II (efficacy), and Phase III
(capturing desired initial indications). This book walks the reader
through all aspects of the process, which has never been done
before in a single reference. With the rise of antibiotic
resistance and the increasing view that a crisis may be looming in
infectious diseases, there are strong signs of renewed emphasis in
antibiotic research. The purpose of the handbook is to offer a
detailed overview of all aspects of the problem posed by antibiotic
discovery and development.
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