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Fluorescence In Situ Hybridization (FISH) - Application Guide (Paperback, Softcover reprint of the original 2nd ed. 2017)
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Fluorescence In Situ Hybridization (FISH) - Application Guide (Paperback, Softcover reprint of the original 2nd ed. 2017)
Series: Springer Protocols Handbooks
Expected to ship within 10 - 15 working days
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This manual offers detailed protocols for fluorescence in situ
hybridization (FISH) and comparative genomic hybridization
approaches, which have been successfully used to study various
aspects of genomic behavior and alterations. Methods using
different probe and cell types, tissues and organisms, such as
mammalians, fish, amphibians (including lampbrush-chromosomes),
insects, plants and microorganisms are described in 57 chapters. In
addition to multicolor FISH procedures and special applications
such as the characterization of marker chromosomes, breakpoints,
cryptic aberrations, nuclear architectures and epigenetic changes,
as well as comparative genomic hybridization studies, this 2nd
edition describes how FISH can be combined with other techniques.
The latter include immunostaining, electron microscopy, single cell
electrophoresis and microdissection. This well-received application
guide provides essential protocols for beginning FISHers and FISH
experts alike working in the fields of human genetics,
microbiology, animal and plant sciences.
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