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Stem Cells in Animal Species: From Pre-clinic to Biodiversity (Hardcover, 2014)
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Stem Cells in Animal Species: From Pre-clinic to Biodiversity (Hardcover, 2014)
Series: Stem Cell Biology and Regenerative Medicine
Expected to ship within 12 - 17 working days
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In recent years, many limits to stem cell research s reliance on
murine models have become evident.Regenerative medicine however,
requires solid intermediate models where the results obtained in
the mouse can be translated and assessed carefully in order to
safely apply them to the human. Divided into three parts, Stem
Cells in Animals: Pre-clinic to Biodiversity focuses on stem cells
in non-murine species. The first part presents an overview of the
different pre-clinical models recently created in other, non-murine
animal species including the porcine model for heart failure, iPSC
in large animal species, Duchenne muscular dystrophy and canine
embryo-derived stem cells and modeling for human diseases. The
second part of the book describes the recent efforts to use stem
cells for preserving endangered species including the snow leopard,
the rhino and coral reefs. From this perspective, stem cells are an
invaluable tool in the preservation of biodiversities. Frozen cells
and gametes can be obtained from animals at risk of extinction as
well as from microorganisms and corals suffering from pollution and
heavy changes in the eco-system. This may allow the generation of
stem cell lines and represents an exciting opportunity to support
and ensure the conservation of precious varieties of living
creatures. This discussion leads easily into the third section
which discusses stem cell banking as a way of safeguarding these
endangered species."
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