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Selected Nitro- and Nitro-Oxy-Polycyclic Aromatic Hydrocarbons (Paperback)
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Selected Nitro- and Nitro-Oxy-Polycyclic Aromatic Hydrocarbons (Paperback)
Series: Environmental Health Criteria, No. 229
Expected to ship within 10 - 15 working days
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This volume studies the risk to the environment and human health
posed by nitroPAHS. Data on the in vivo genotoxicity of nitroPAHs
are available for 15 nitroPAHs. All nitroPAHs that gave positive
results in vivo were also positive in vitro. Four nitroPAHs that
were positive in in vitro genotoxicity tests revealed inconsistent
or inconclusive genotoxicity (2-nitronaphthalene,
5-nitroacenaphthene and 3-nitrofluoranthene) or negative
genotoxicity (2,7-dinitrofluorene; limited validity) results in
vivo. There are no reports on the effects of individual nitroPAHs
on humans. As would be expected, since nitroPAHs occur in complex
mixtures in the atmosphere and exhaust, the exact contribution of
nitroPAHs to the adverse health consequences of exposure to
polluted atmospheres and to exhaust cannot be elucidated.
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