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Ribosomal Proteins & Protein Engineering - Design, Selection & Applications (Hardcover)
Loot Price: R2,873
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Ribosomal Proteins & Protein Engineering - Design, Selection & Applications (Hardcover)
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Ribosome is an important cellular organelle that is necessary for
the basic cellular process, protein synthesis. Furthermore,
ribosomal protein is a group of proteins that is important in
biomedical research. The authors of this book present and review
important data on ribosomal proteins, important in tropical
diseases such as malaria and tuberculosis. In addition, some
functions of ribosomal proteins, other than translation, are called
extraribosomal function or extraribosomal activity. In this book,
the extraribosomal functions of ribosomal protein S19 (RPS19) is
discussed in detail. Other chapters in this book examine the
structures of the free and bound forms of proteins that have
experimentally been found to be essential for the first steps of
ribosome assembly. A summary of ribosomal protein mutations
generated in eukaryotes is also provided and their proposed roles
in the control of cell growth and proliferation, as well as their
impact in human diseases. Important challenges we face in
explaining life from the genome and proteome viewpoint is also
discussed, including how to measure a living protein/RNA/DNA, how
to restore the missing relation cross generations and how to
correlate structure with function. Finally, the authors suggest
possible solutions for such challenges.
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