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Lung Cancer Metastasis - Novel Biological Mechanisms and Impact on Clinical Practice (Hardcover, 2010 ed.)
Loot Price: R4,289
Discovery Miles 42 890
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(34%)
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Lung Cancer Metastasis - Novel Biological Mechanisms and Impact on Clinical Practice (Hardcover, 2010 ed.)
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Lung cancer is the leading cause of cancer-related mortality.
Metastatic lung cancer is responsible for more than ninety percent
of lung cancer related deaths. However, relatively little progress
has been made in understanding the process of lung cancer
metastasis. The two main aims of this book are a) to introduce
clinical aspects to basic scientists and basic molecular and
cellular concepts to clinical investigators, in order to promote
collaboration and foster much needed translational research; and b)
to introduce new and emerging concepts and approaches in metastasis
research to lung cancer research community at large. In this
attempt, the book will cover a broad spectrum of subjects ranging
from the current trends in the clinical management of the
metastatic disease, to the systems biology approach for gaining
insights into the mechanisms of metastasis. Some of the subjects
covered will include: defining basic hallmarks of a metastatic
cell, the concept of tumor stem cells, epithelial-mesenchymal
transitions, evasion of immune-surveillance, tumor-stromal
interactions, angiogenesis, molecular imaging and biomarker
discovery.
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