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Fortschritte der Chemie organischer Naturstoffe - Progress in the Chemistry of Organic Natural Products (Paperback, Softcover reprint of the original 1st ed. 1999)
Loot Price: R2,832
Discovery Miles 28 320
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Fortschritte der Chemie organischer Naturstoffe - Progress in the Chemistry of Organic Natural Products (Paperback, Softcover reprint of the original 1st ed. 1999)
Series: Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products, 77
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The condensed tannins (syn. polymeric proanthocyanidins) represent
a major group of phenolic compounds in woody and some herbaceous
plants (1-3). Their exceptional concentrations in the barks and
heartwoods of a variety of tree species have resulted in their
commercial extraction with the initial objective of applying the
extracts in leather manufacture (4). Essentially all of their
biological significance, e. g. the protection of plants from
insects, diseases and herbivores, and most of the current, e. g.
leather manufacture, and also most promising new uses, e. g.
pharmaceuticals or wood preservatives, rest on their com plexation
with other biopolymers like proteins and carbohydrates, or metal
ions (5, 6). Increasing attention has thus been directed to
understanding their conformation and conformational flexibility
(7-20) in order to explain their biological activity and to provide
a basis for further development of uses for these renewable
phenolic compounds. Recent developments have also been initiated by
the growing realization that the condensed tannins may additionally
be credited for the profound health-beneficial properties of tea,
fruit juices and red wine. This is mainly due to their in vitro
radical scavenging (21) or antioxidant (22) biological properties,
while the polymeric proanthocyanidins in red wine have been
implicated in protection against cardiovascular disorders (23), e.
g. the "French paradox" (24-26). Collectively these 'positive'
characteristics of the polymeric proanthocyanidins have transformed
"a relatively unattractive and therefore neglected area of study"
(27) into, yet again, a fashionable research field."
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