Microarray technology provides researchers in the life sciences
with a revolutionary tool for measuring gene expression. However,
this highly developed process involves multiple steps, from sample
selection to data analysis, each susceptible to potentially costly
errors. Without sound quality control, experimental microarrays may
produce useless or, even worse, misleading results.
Microarray Quality Control provides a comprehensive resource for
ensuring quality control in every step of this complex process.
From experimental design to data processing, analysis, and
interpretation, the emphasis in this text remains on practical
advice for each stage of planning and running a microarray study.
Chapters cover:
- Quality of biological samples
- Quality of DNA
- Hybridization protocols Scanning
- Data acquisition
- Image analysis
- Data analysis
Written for the broad group of workers-biologists,
mathematicians, statisticians, engineers, physicians, and
computational scientists-involved in microarray studies, Microarray
Quality Control features a straightforward style easily accessed by
various disciplines. Useful checklists and tips help ensure the
integrity of results, and each chapter contains a thorough review
of pertinent literature.
The only complete, systematic treatment of the topic available,
Microarray Quality Control offers students and practitioners an
invaluable resource for improving experimental quality and
efficiency.
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