Death Receptors in Cancer Therapy (Paperback, Softcover reprint of hardcover 1st ed. 2005)

An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Cancer Drug Discovery and Development
Release date:	November 2010
First published:	2005
Editors:	Wafik S ElDeiry
Dimensions:	254 x 178 x 20mm (L x W x T)
Format:	Paperback
Pages:	374
Edition:	Softcover reprint of hardcover 1st ed. 2005
ISBN-13:	978-1-61737-401-2
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-61737-401-6
Barcode:	9781617374012

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