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Nutritional Genomics - The Impact of Dietary Regulation of Gene Function on Human Disease (Hardcover)
Loot Price: R5,268
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Nutritional Genomics - The Impact of Dietary Regulation of Gene Function on Human Disease (Hardcover)
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The notion of matching diet with an individual's genetic makeup is
transforming the way the public views nutrition as a means of
managing health and preventing disease. To fulfill the promise of
nutritional genomics, researchers are beginning to reconcile the
diverse properties of dietary factors with our current knowledge of
genome structure and gene function. What is emerging is a complex
system of interactions that make the human genome exquisitely
sensitive to our nutritional environment. Nutritional Genomics: The
Impact of Dietary Regulation of Gene Function on Human Disease
provides an integrated view of how genomic and epigenetic processes
modulate the impact of dietary factors on health. Written as a
resource for researchers, nutrition educators, and policy makers,
this book contains the latest scientific findings on the mechanisms
of action underlying diet-genome interactions. It presents a unique
perspective on the fundamentals of nutritional genomics from
genomics, transcriptomics, proteomics, and metabolomics.
Contributing authors introduce the important areas of cell
signaling and transduction, the intricate regulation of gene
expression, and alteration of gene-linked chronic diseases, such as
obesity-induced inflammation, insulin resistance, metabolic
syndrome, cardiovascular disease, and cancer. The authors detail
significant areas of interest within nutritional genomics-including
plant-based foods as epigenetic modifiers of gene function and the
effects of bioactive phytochemicals on inherited genotype and
expressed phenotypes. They also discuss the role of vitamin D in
various cancer risks and the gastrointestinal tract as a defense
system. Given the key role played by agriculture and the food
industry to produce foods to meet personalized health needs, the
book also addresses agricultural breeding efforts to enhance
nutritional value and the use of technology to increase bioactive
ingredients in the food supply. The final chapters discuss
manufacturing practices and novel processing techniques for
retention of nutrients and bioactive components, as well as the
need for regulatory oversight and proper labeling to establish
assurance of safety and benefit. An excellent resource for this
exciting field, the book identifies future directions for research
and opportunities for improving global health and wellness by
preventing, delaying, or mitigating chronic diseases with diet.
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