Plague is a terrifying mystery.
In the Middle Ages, it wiped out 40 million people -- 40 percent
of the total population in Europe. Seven hundred years earlier, the
Justinian Plague destroyed the Byzantine Empire and ushered in the
Middle Ages. The plague of London in the seventeenth century killed
more than 1,000 people a day. In the early twentieth century,
plague again swept Asia, taking the lives of 12 million in India
alone.
Even more frightening is what it could do to us in the near
future. Before the collapse of the Soviet Union, Russian scientists
created genetically altered, antibiotic-resistant and
vaccine-resistant strains of plague that can bypass the human
immune system and spread directly from person to person. These
weaponized strains still exist, and they could be replicated in
almost any laboratory.
Wendy Orent's "Plague" pieces together a fascinating and
terrifying historical whodunit. Drawing on the latest research in
labs around the world, along with extensive interviews with
American and Soviet plague experts, Orent offers nothing less than
a biography of a disease. Plague helped bring down the Roman Empire
and close the Middle Ages; it has had a dramatic impact on our
history, yet we still do not fully understand its own evolution.
Orent's retelling of the four great pandemics makes for gripping
reading and solves many puzzles. Why did some pandemics jump from
person to person, while others relied on insects as carriers? Why
are some strains more virulent than others? Orent reveals the key
differences among rat-based, prairie dog-based, and marmot-based
plague. The marmots of Central Asia, in particular, have long been
hosts to the most virulent and frightening form of the disease, a
form that can travel around the world in the blink of an eye.
From its ability to hide out in the wild, only to spring back
into humanity with a terrifying vengeance, to its elusive capacity
to develop suddenly greater virulence and transmissibility, plague
is a protean nightmare. To make matters worse, Orent's disturbing
revelations about the former Soviet bioweapon programs suggest that
the nightmare may not be over. "Plague" is chilling reading at the
dawn of a new age of bioterrorism.
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