ODE/PDE Alpha-Synuclein Models for Parkinson's Disease discusses a
mechanism for the evolution of Parkinson's Disease (PD) based on
the dynamics of the protein a-synuclein, a monomer that has been
implicated in this disease. Specifically, a-synuclein morphs and
aggregates into a polymer that can interfere with functioning
neurons and lead to neurodegenerative pathology. This book first
demonstrates computer-based implementation of a prototype ODE/PDE
model for the dynamics of the a-synuclein monomer and polymer, and
then details the methodology for the numerical integration of
ODE/PDE systems which can be applied to computer-based analyses of
alternative models based on the reader's interest. This book
facilitates immediate computer use for research without the
necessity to first learn the basic concepts of numerical analysis
for ODE/PDEs and programming algorithms
General
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